Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1419899 | 0.84 | KDM4E (0.50) | HTR2AHTR2CKCNH2NUDT1ALDH1A1 | |
| SCHEMBL9091086 | 0.82 | HTR2A (0.46) | HTR2AHTR2CKCNH2NUDT1SSTR4 | |
| Lithium SCHEMBL31115344 | 0.82 | DHODH (0.49) | HTR2AHTR2CKCNH2NUDT1ALDH1A1 | |
| SCHEMBL1756867 | 0.82 | HTR2A (0.43) | HTR2AHTR2CKCNH2NUDT1SSTR4 | |
| Hydrochloric Acid SCHEMBL9091092 | 0.82 | DHODH (0.49) | HTR2AHTR2CKCNH2NUDT1ALDH1A1 | |
| SCHEMBL1420264 | 0.82 | MKNK1 (0.47) | HTR2AHTR2CKCNH2NUDT1ALDH1A1 | |
| SCHEMBL20330342 | 0.81 | TP53 (0.43) | HTR2AHTR2CKCNH2SSTR4IRAK4 | |
| SCHEMBL1878367 | 0.81 | KDM4E (0.49) | HTR2AHCRTR2ALDH1A1KDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL14837018 | 0.81 | HTR2A (0.45) | HTR2AHTR2CKCNH2NUDT1SSTR4 | |
| Hydrochloric Acid SCHEMBL30521486 | 0.81 | MKNK1 (0.46) | HTR2AHTR2CKCNH2NUDT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132870-A1 | CHEMICAL COMPOUNDS AND USES THEREOF | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.4) LIMITED (GB) | 2025-06-26 | — | — | WO | disclosed |
| WO-2022261257-A1 | STAPLED PEPTIDES AND METHODS THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2022-12-15 | — | — | WO | disclosed |
| WO-2005010001-A1 | NICOTINAMIDE DERIVATIVES USEFUL AS PDEA4 INHIBITORS | PFIZER LIMITED (GB) | 2005-02-03 | — | — | WO | disclosed |