Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | BRD2 | P25440 | 1/20 | 0.41 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.41 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.38 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 4/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18038264 | 0.84 | P2RX7 (0.49) | HTR2AIRAK4HTR2CKCNH2SSTR4 | |
| SCHEMBL20312855 | 0.83 | SMN1; SMN2 (0.46) | TP53HTR2AIRAK4HTR2CKCNH2 | |
| SCHEMBL8313115 | 0.81 | HTR2A (0.43) | HTR2AIRAK4HTR2CKCNH2SSTR4 | |
| SCHEMBL1878367 | 0.81 | KDM4E (0.49) | GAAHTR2AIRAK4 | |
| SCHEMBL1419899 | 0.80 | KDM4E (0.50) | HTR2AHTR2CKCNH2 | |
| SCHEMBL1756867 | 0.78 | HTR2A (0.43) | HTR2AIRAK4HTR2CKCNH2SSTR4 | |
| SCHEMBL1420264 | 0.78 | MKNK1 (0.47) | HTR2AIRAK4HTR2CKCNH2ADRA1A | |
| SCHEMBL9091086 | 0.78 | HTR2A (0.46) | HTR2AIRAK4HTR2CKCNH2SSTR4 | |
| Lithium SCHEMBL31115344 | 0.78 | DHODH (0.49) | HTR2AHTR2CKCNH2 | |
| Hydrochloric Acid SCHEMBL9091092 | 0.78 | DHODH (0.49) | HTR2AHTR2CKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132870-A1 | CHEMICAL COMPOUNDS AND USES THEREOF | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.4) LIMITED (GB) | 2025-06-26 | — | — | WO | disclosed |
| WO-2018119263-A1 | HETEROCYCLIC COMPOUNDS DERIVATIVES AS PD-L1 INTERNALIZATION INDUCERS | INCYTE CORPORATION (US) | 2018-06-28 | — | — | WO | disclosed |