Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | PREP | P48147 | 5/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4847115 | 0.88 | CHRM2 (0.45) | CHRM2CHRM1CHRM3PREPEPHX1 | |
| SCHEMBL3050914 | 0.88 | CHRM2 (0.45) | CHRM2CHRM1CHRM3PREPEPHX1 | |
| SCHEMBL4840543 | 0.88 | CHRM2 (0.45) | CHRM2CHRM1CHRM3PREPEPHX1 | |
| SCHEMBL8337646 | 0.88 | CHRM2 (0.45) | CHRM2CHRM1CHRM3PREPEPHX1 | |
| SCHEMBL14053968 | 0.88 | CHRM2 (0.45) | CHRM2CHRM1CHRM3PREPEPHX1 | |
| SCHEMBL4795338 | 0.88 | CHRM2 (0.45) | CHRM2CHRM1CHRM3PREPEPHX1 | |
| SCHEMBL15116700 | 0.88 | CHRM2 (0.45) | CHRM2CHRM1CHRM3PREPEPHX1 | |
| SCHEMBL20221211 | 0.88 | CHRM2 (0.45) | CHRM2CHRM1CHRM3PREPEPHX1 | |
| SCHEMBL1336739 | 0.88 | CHRM2 (0.45) | CHRM2CHRM1CHRM3PREPEPHX1 | |
| SCHEMBL27272431 | 0.88 | CHRM2 (0.45) | CHRM2CHRM1CHRM3PREPEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071454-A2 | SUBSTITUTED AZETIDINE COMPOUNDS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | GUILFORD PHARMACEUTICALS INC. (US) | 2004-08-26 | — | — | WO | disclosed |