Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.41 |
| ▸ | ITGAV | P06756 | 8/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.39 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.37 |
| ▸ | ITGB6 | P18564 | 2/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6260649 | 0.86 | ITGAV (0.40) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL6260655 | 0.86 | ITGAV (0.40) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL8333617 | 0.86 | ITGAV (0.40) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL6260652 | 0.81 | ITGAV (0.40) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL12807021 | 0.81 | ITGAV (0.42) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL6219556 | 0.80 | ITGB3 (0.43) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL6221119 | 0.78 | ITGB3 (0.41) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL5847757 | 0.78 | ITGAV (0.42) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL5847742 | 0.73 | ITGAV (0.56) | ITGB3ITGAVITGB5ITGB6ITGA2B | |
| SCHEMBL31063405 | 0.70 | ITGAV (0.38) | ITGB3ITGAVITGB1ITGA5ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058760-A1 | THIAZOLE COMPOUNDS AS INTEGRIN RECEPTOR ANTAGONISTS DERIVATIVES | PHARMACIA CORPORATION (US) | 2004-07-15 | — | — | WO | disclosed |