Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 13/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.33 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | IMPDH1 | P20839 | 7/20 | 0.32 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6279232 | 0.89 | GAA (0.34) | IMPDH2GSK3BMEN1KMT2AGAA | |
| SCHEMBL1487574 | 0.87 | IMPDH2 (0.34) | IMPDH2GSK3BMEN1KMT2AGAA | |
| SCHEMBL22591311 | 0.75 | GSK3B (0.33) | IMPDH2GSK3BMEN1KMT2AGAA | |
| SCHEMBL13753911 | 0.73 | AAK1 (0.33) | IMPDH2IMPDH1ELANE | |
| SCHEMBL13745538 | 0.71 | BRD4 (0.40) | GSK3BMEN1KMT2A | |
| SCHEMBL1614459 | 0.71 | DYRK1A (0.38) | IMPDH2MEN1KMT2AGAAIMPDH1 | |
| SCHEMBL29086594 | 0.70 | ELANE (0.59) | GAAELANE | |
| SCHEMBL29890000 | 0.70 | ELANE (0.59) | GAAELANE | |
| SCHEMBL13746216 | 0.68 | PTGDR2 (0.32) | IMPDH2GSK3BIMPDH1HSD17B10 | |
| SCHEMBL1487563 | 0.67 | DYRK1A (0.55) | IMPDH2MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078756-A2 | JNK INHIBITORS | EISAI CO., LTD. (JP) | 2004-09-16 | — | — | WO | disclosed |