Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8311237 | 0.91 | RXRA (0.32) | — | |
| SCHEMBL8312121 | 0.77 | — | — | |
| SCHEMBL31028079 | 0.72 | CYP19A1 (0.53) | — | |
| SCHEMBL4688774 | 0.72 | CYP19A1 (0.56) | ALDH1A1MAPT | |
| SCHEMBL31028072 | 0.72 | CYP19A1 (0.56) | ALDH1A1MAPT | |
| SCHEMBL4688568 | 0.72 | CYP19A1 (0.56) | ALDH1A1MAPT | |
| SCHEMBL4688567 | 0.72 | CYP19A1 (0.56) | ALDH1A1MAPT | |
| SCHEMBL8309668 | 0.72 | TP53 (0.36) | — | |
| SCHEMBL7953943 | 0.71 | MAPT (0.50) | ALDH1A1MAPTMAPK1 | |
| SCHEMBL7953939 | 0.71 | MAPT (0.50) | ALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933351-A1 | Tricyclic retinoids, methods for their production and use | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1999-08-04 | — | — | EP | disclosed |
| EP-0933350-A1 | Tricyclic retinoids, methods for their production and use | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1999-08-04 | — | — | EP | disclosed |