Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 2/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | CCR3 | P51677 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL250507 | 0.91 | BCHE (0.61) | BCHEMEN1TSHRKMT2ASIGMAR1 | |
| SCHEMBL1034422 | 0.89 | BCHE (0.68) | BCHEMEN1TSHRKMT2ASIGMAR1 | |
| SCHEMBL186785 | 0.88 | BCHE (0.67) | BCHEMEN1TSHRKMT2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL14166026 | 0.88 | BCHE (0.67) | BCHEMEN1TSHRKMT2ASIGMAR1 | |
| SCHEMBL4135213 | 0.88 | BCHE (0.67) | BCHEMEN1TSHRKMT2ASIGMAR1 | |
| SCHEMBL8550490 | 0.86 | BCHE (0.65) | BCHEMEN1KMT2AACHEOPRK1 | |
| Hydrochloric Acid SCHEMBL9380707 | 0.86 | BCHE (0.65) | BCHEMEN1TSHRKMT2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL22587709 | 0.86 | BCHE (0.65) | BCHEMEN1TSHRKMT2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL8556315 | 0.85 | MEN1 (0.65) | BCHEMEN1KMT2AACHEOPRK1 | |
| Hydrochloric Acid SCHEMBL10969823 | 0.85 | BCHE (0.64) | BCHEMEN1TSHRKMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540914-B1 | 2-Aminomethylchromans as active ingredients in medicaments for the treatment of diseases of the central nervous system | BAYER AG (DE) | 1999-06-02 | — | — | EP | disclosed |
| EP-0540914-A1 | 2-Aminomethylchromans as active ingredients in medicaments for the treatment of diseases of the central nervous system | BAYER AG (DE) | 1993-05-12 | — | — | EP | disclosed |