Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.61 |
| ▸ | MAOB | P27338 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8313882 | 0.91 | BCHE (0.70) | BCHEOPRK1MEN1TSHRKMT2A | |
| SCHEMBL28408852 | 0.88 | BCHE (0.58) | BCHEMAOBALDH1A1OPRK1 | |
| SCHEMBL2893650 | 0.88 | BCHE (0.60) | BCHEMAOB | |
| SCHEMBL22721874 | 0.88 | BCHE (0.58) | BCHEMAOBALDH1A1OPRK1 | |
| SCHEMBL28412274 | 0.88 | BCHE (0.58) | BCHEMAOBALDH1A1OPRK1 | |
| SCHEMBL3206960 | 0.88 | BCHE (0.60) | BCHEMAOB | |
| SCHEMBL9685669 | 0.88 | BCHE (0.60) | BCHEMAOB | |
| SCHEMBL10508986 | 0.87 | BCHE (0.56) | BCHEMAOBS1PR5SIGMAR1 | |
| SCHEMBL759143 | 0.87 | CARM1 (0.57) | BCHEMAOBOPRK1S1PR5MEN1 | |
| SCHEMBL765918 | 0.87 | CARM1 (0.57) | BCHEMAOBOPRK1S1PR5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188251-B1 | ARYLSULFONAMIDES WITH ANALGESIC ACTIVITY | BOEHRINGER INGELHEIM INT (DE) | 2015-04-29 | — | — | EP | disclosed |
| EP-2061779-B1 | ARYL SULFONAMIDES WITH AN ANALGESIC ACTION | BOEHRINGER INGELHEIM INT (DE) | 2013-11-06 | — | — | EP | disclosed |
| EP-2402329-A1 | Analgetic phenylsulphonamides | Boehringer Ingelheim International GmbH (DE) | 2012-01-04 | — | — | EP | disclosed |
| EP-2284166-A1 | Arylsulfonamides with analgetic activity | Boehringer Ingelheim International GmbH (DE) | 2011-02-16 | — | — | EP | disclosed |
| EP-2188251-A1 | ARYLSULFONAMIDES WITH ANALGESIC ACTIVITY | Boehringer Ingelheim International GmbH (DE) | 2010-05-26 | — | — | EP | disclosed |
| WO-2009021946-A1 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-02-19 | — | — | WO | disclosed |
| EP-2025675-A1 | Arylsulfonamides with analgetic activity | Boehringer Ingelheim International GmbH (DE) | 2009-02-18 | — | — | EP | disclosed |