Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8314082 | 1.00 | AGTR1 (0.70) | AGTR1 | |
| SCHEMBL7270382 | 0.94 | AGTR1 (0.71) | AGTR1 | |
| SCHEMBL7270388 | 0.94 | AGTR1 (0.71) | AGTR1 | |
| SCHEMBL8309697 | 0.91 | AGTR1 (0.67) | AGTR1 | |
| SCHEMBL8309702 | 0.91 | AGTR1 (0.67) | AGTR1 | |
| SCHEMBL8311594 | 0.89 | AGTR1 (0.71) | AGTR1 | |
| SCHEMBL7275787 | 0.89 | AGTR1 (0.71) | AGTR1 | |
| SCHEMBL8311598 | 0.89 | AGTR1 (0.71) | AGTR1 | |
| SCHEMBL7275800 | 0.89 | AGTR1 (0.71) | AGTR1 | |
| SCHEMBL7268126 | 0.89 | AGTR1 (0.70) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955294-A2 | Imidazolyl-alkenoic acid | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-10 | — | — | EP | disclosed |
| US-5418250-A | Hypotensive | SMITHKLINE BEECHAM CORPORATION (US) | 1995-05-23 | — | — | US | disclosed |