SCHEMBL8314213

SCHEMBL8314213

CCC(CC)(CO)CS(=O)(=O)N=CN(C)C

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8314211 1.00 LMNA (0.31) LMNAGAA
SCHEMBL8558168 0.85
SCHEMBL8558165 0.85
SCHEMBL8314533 0.83
SCHEMBL8314531 0.83
SCHEMBL8313127 0.81 LMNA (0.30) LMNAGAA
SCHEMBL8313129 0.81 LMNA (0.30) LMNAGAA
SCHEMBL8314794 0.81
SCHEMBL8314789 0.81
SCHEMBL8314503 0.79 LMNA (0.33) LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0562439-B1 Triazolopyridazines as antioasthmatics TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1999-06-09 EP disclosed
EP-0620224-B1 Triazolopyridazine derivatives, their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1998-07-15 EP disclosed
US-5492909-A ANTI-PLATELET ACTIVATING FACTOR, ANTIALLERGEN, ANTIASTHMATIC TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-02-20 US disclosed
US-5491145-A ANTIASTHMA, ANTI-PLATELET ACTIVATING FACTOR BRONCHOCONSTRICTION-INHIBITING AGENTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-02-13 US disclosed
US-5482939-A ANTI-PLATELET ACTIVATING FACTOR ACTIVITIES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-01-09 US disclosed
US-5389633-A ANTIASTHMATIC AGENTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1995-02-14 US disclosed
EP-0620224-A1 Triazolopyridazine derivatives, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-10-19 EP disclosed
EP-0562439-A1 Triazolopyridazines as antioasthmatics TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-09-29 EP disclosed
EP-0562440-A1 Imidazopyridazines as antiasthmatics TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-09-29 EP disclosed