Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | AS3MT | Q9HBK9 | 1/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 11/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12983603 | 0.85 | MCHR1 (0.70) | MCHR1CYP3A4 | |
| SCHEMBL9616130 | 0.78 | ALOX5 (0.61) | ALOX5PTGS1PTGS2MEN1KMT2A | |
| SCHEMBL12984268 | 0.78 | MCHR1 (0.82) | MCHR1CYP3A4 | |
| SCHEMBL25634016 | 0.78 | MCHR1 (0.74) | MCHR1HRH3CYP3A4 | |
| SCHEMBL8757571 | 0.78 | MEN1 (0.49) | MEN1NPC1RAB9AKMT2AMAOB | |
| SCHEMBL8758362 | 0.78 | AS3MT (0.51) | MEN1NPC1RAB9AKMT2AMAOB | |
| SCHEMBL12927541 | 0.78 | MCHR1 (0.81) | MCHR1CYP3A4 | |
| SCHEMBL15889558 | 0.78 | MCHR1 (0.61) | MCHR1CYP3A4 | |
| SCHEMBL25634015 | 0.77 | MCHR1 (0.74) | MCHR1CYP3A4 | |
| Hydrochloric Acid SCHEMBL8757755 | 0.77 | AS3MT (0.50) | MEN1NPC1RAB9AKMT2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690050-B1 | (Thia)cycloalkyl(b) indole derivatives as 5-lipoxygenase inhibitors | ADIR (FR) | 1999-11-17 | — | — | EP | claimed |
| EP-0690050-B1 | (Thia)cycloalkyl(b) indole derivatives as 5-lipoxygenase inhibitors | ADIR (FR) | 1999-11-17 | — | — | EP | disclosed |