Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8313918 | 0.99 | IKBKB (0.65) | IKBKBCHUK | |
| SCHEMBL8314529 | 0.93 | IKBKB (0.63) | IKBKBCHUK | |
| SCHEMBL8313912 | 0.88 | IKBKB (0.75) | IKBKBCHUK | |
| SCHEMBL8313405 | 0.87 | IKBKB (0.74) | IKBKBCHUK | |
| SCHEMBL14063893 | 0.86 | IKBKB (0.54) | IKBKBCHUK | |
| SCHEMBL8311423 | 0.86 | IKBKB (0.67) | IKBKBCHUK | |
| SCHEMBL8311421 | 0.85 | IKBKB (0.66) | IKBKBCHUK | |
| SCHEMBL8312614 | 0.85 | IKBKB (0.66) | IKBKBCHUK | |
| SCHEMBL8311727 | 0.85 | IKBKB (0.63) | IKBKBCHUK | |
| SCHEMBL8253604 | 0.84 | IKBKB (0.52) | IKBKBCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7429599-B2 | Methods for treating or preventing an inflammatory or metabolic condition or inhibiting JNK | SIGNAL PHARMACEUTICALS, LLC (US) | 2008-09-30 | — | — | US | disclosed |
| US-7429599-B2 | Methods for treating or preventing an inflammatory or metabolic condition or inhibiting JNK | SIGNAL PHARMACEUTICALS, LLC (US) | 2008-09-30 | — | — | US | disclosed |
| WO-2004084901-A1 | METHODS FOR TREATING OR PREVENTING AN INFLAMMATORY OR METABOLIC CONDITION BY INHIBITING JNK | SIGNAL PHARMACEUTICALS, LLC (US) | 2004-10-07 | — | — | WO | disclosed |