Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 3/20 | 0.54 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.54 |
| ▸ | OXTR | P30559 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8318107 | 0.92 | AVPR2 (0.65) | AVPR2AVPR1A | |
| SCHEMBL8312611 | 0.91 | AVPR1A (0.53) | AVPR2AVPR1AOXTR | |
| SCHEMBL7409772 | 0.91 | AVPR2 (0.63) | AVPR2AVPR1A | |
| SCHEMBL8312759 | 0.90 | AVPR1A (0.55) | AVPR2AVPR1A | |
| SCHEMBL8315722 | 0.89 | AVPR1A (0.64) | AVPR2AVPR1AOXTR | |
| SCHEMBL8318709 | 0.88 | AVPR2 (0.54) | AVPR2AVPR1A | |
| SCHEMBL8314568 | 0.85 | AVPR1A (0.58) | AVPR2AVPR1A | |
| SCHEMBL8317245 | 0.85 | AVPR2 (0.46) | AVPR2AVPR1AOXTR | |
| SCHEMBL8314000 | 0.85 | AVPR1A (0.56) | AVPR2AVPR1AOXTR | |
| SCHEMBL7333870 | 0.85 | AVPR2 (0.64) | AVPR2AVPR1AOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636625-B1 | Tricyclic diazepines vasopressin and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1999-01-27 | — | — | EP | disclosed |