Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 12/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 11/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | GLP1R | P43220 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | OXTR | P30559 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315247 | 0.87 | NPSR1 (0.44) | AVPR2AVPR1AALDH1A1RAB9A | |
| SCHEMBL8314766 | 0.85 | AVPR2 (0.54) | AVPR2AVPR1AOXTR | |
| SCHEMBL7333870 | 0.83 | AVPR2 (0.64) | AVPR2AVPR1AALDH1A1OXTRNPC1 | |
| SCHEMBL8318107 | 0.81 | AVPR2 (0.65) | AVPR2AVPR1A | |
| SCHEMBL7341288 | 0.78 | AVPR2 (0.68) | AVPR2AVPR1AOXTR | |
| SCHEMBL8318709 | 0.78 | AVPR2 (0.54) | AVPR2AVPR1ANPC1RAB9A | |
| SCHEMBL8312759 | 0.77 | AVPR1A (0.55) | AVPR2AVPR1A | |
| SCHEMBL7337562 | 0.77 | AVPR2 (0.44) | AVPR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7334076 | 0.77 | AVPR2 (0.68) | AVPR2AVPR1AOXTRNPC1RAB9A | |
| SCHEMBL7409772 | 0.76 | AVPR2 (0.63) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636625-B1 | Tricyclic diazepines vasopressin and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1999-01-27 | — | — | EP | disclosed |