SCHEMBL8314802

SCHEMBL8314802

[CH2]CCC(=O)NC(C)CC

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.49
HPGD P15428 1/20 0.46
MMP1 P03956 1/20 0.45
MMP2 P08253 1/20 0.45
MMP3 P08254 1/20 0.45
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43
PKM P14618 1/20 0.41
MAPT P10636 2/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
FAAH O00519 1/20 0.39
MAPK1 P28482 1/20 0.39
EPHX1 P07099 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7553234 0.84 FAAH (0.52) SMN1; SMN2HPGDMMP1MMP2MMP3
SCHEMBL7558688 0.84 FAAH (0.52) SMN1; SMN2HPGDMMP1MMP2MMP3
SCHEMBL7552630 0.84 FAAH (0.52) SMN1; SMN2HPGDMMP1MMP2MMP3
SCHEMBL7555477 0.84 FAAH (0.52) SMN1; SMN2HPGDMMP1MMP2MMP3
SCHEMBL23480155 0.82 SMN1; SMN2 (0.51) SMN1; SMN2HPGDMMP1MMP2MMP3
SCHEMBL8437464 0.82
SCHEMBL7262590 0.82 SMN1; SMN2 (0.51) SMN1; SMN2HPGDMMP1MMP2MMP3
SCHEMBL7343969 0.79
SCHEMBL799655 0.78 SMN1; SMN2 (0.53) SMN1; SMN2HPGDMMP1MMP2MMP3
SCHEMBL18023464 0.78 SMN1; SMN2 (0.49) SMN1; SMN2HPGDMMP1MMP2MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0958292-A1 4-(3-HETEROCYCLYL-1-BENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1999-11-24 EP disclosed
WO-1998031682-A1 4-(3-HETEROCYCLYL-1-BENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1998-07-23 WO disclosed