Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 6/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ANO1 | Q5XXA6 | 3/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.30 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.30 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6597036 | 0.83 | CNR1 (0.33) | MAOB | |
| SCHEMBL8316231 | 0.79 | MAOB (0.46) | F2RL3MAOB | |
| SCHEMBL8310428 | 0.79 | F2RL3 (0.33) | F2RL3 | |
| SCHEMBL8316881 | 0.79 | MRGPRX4 (0.52) | MRGPRX4 | |
| Water SCHEMBL8314845 | 0.79 | F2RL3 (0.32) | F2RL3 | |
| SCHEMBL8314160 | 0.77 | MRGPRX4 (0.48) | MAOBMRGPRX4CYP26A1 | |
| SCHEMBL6599726 | 0.77 | F2RL3 (0.31) | F2RL3 | |
| SCHEMBL7472096 | 0.77 | F2RL3 (0.32) | F2RL3 | |
| SCHEMBL8315203 | 0.75 | PDE9A (0.31) | MAOBALOX5 | |
| SCHEMBL7480046 | 0.75 | F2RL3 (0.31) | F2RL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528337-B1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-10-20 | — | — | EP | disclosed |
| US-5296495-A | Antiallergens, antiinflammatory | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0528337-A1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |