Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | F2RL3 | Q96RI0 | 5/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8316881 | 0.83 | MRGPRX4 (0.52) | — | |
| SCHEMBL8314160 | 0.81 | MRGPRX4 (0.48) | MAOBMAOA | |
| SCHEMBL8311107 | 0.81 | CHRM2 (0.41) | MAOBF2RL3 | |
| SCHEMBL8311729 | 0.81 | F2RL3 (0.35) | MAOBF2RL3 | |
| SCHEMBL8314965 | 0.79 | F2RL3 (0.35) | MAOBF2RL3 | |
| SCHEMBL6599597 | 0.78 | F2RL3 (0.33) | MAOBF2RL3 | |
| SCHEMBL8314208 | 0.77 | F2RL3 (0.36) | MAOBF2RL3 | |
| SCHEMBL1080157 | 0.77 | F2RL3 (0.36) | MAOBF2RL3 | |
| SCHEMBL6598601 | 0.76 | F2RL3 (0.38) | F2RL3 | |
| SCHEMBL8314939 | 0.76 | MAOB (0.34) | MAOBMAOAF2RL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528337-B1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-10-20 | — | — | EP | disclosed |
| US-5296495-A | Antiallergens, antiinflammatory | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0528337-A1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |