Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 7/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7331634 | 0.85 | AVPR1A (0.46) | MEN1KMT2AAVPR2AVPR1AALDH1A1 | |
| SCHEMBL8628737 | 0.83 | MEN1 (0.45) | MEN1KMT2AAVPR2AVPR1AALDH1A1 | |
| SCHEMBL7360343 | 0.83 | AVPR1A (0.44) | MEN1KMT2AAVPR2AVPR1AALDH1A1 | |
| SCHEMBL7339596 | 0.82 | AVPR2 (0.49) | MEN1KMT2AAVPR2AVPR1AMAPT | |
| SCHEMBL7333493 | 0.79 | AVPR1A (0.48) | AVPR2AVPR1A | |
| SCHEMBL8315803 | 0.79 | AVPR2 (0.46) | AVPR2AVPR1AMAPT | |
| SCHEMBL7340153 | 0.74 | AVPR1A (0.43) | MEN1KMT2AAVPR2AVPR1AALDH1A1 | |
| SCHEMBL7332088 | 0.74 | AVPR2 (0.50) | MEN1KMT2AAVPR2AVPR1AMAPT | |
| SCHEMBL13403230 | 0.72 | AVPR1A (0.53) | KMT2AAVPR2AVPR1AALDH1A1SMN1; SMN2 | |
| SCHEMBL3553869 | 0.71 | AVPR1A (0.44) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636625-B1 | Tricyclic diazepines vasopressin and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1999-01-27 | — | — | EP | disclosed |