Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | AVPR2 | P30518 | 6/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7340153 | 0.91 | AVPR1A (0.43) | MEN1KMT2AAVPR2AVPR1AALDH1A1 | |
| SCHEMBL8315244 | 0.83 | MEN1 (0.47) | MEN1KMT2AAVPR2AVPR1AALDH1A1 | |
| SCHEMBL7339252 | 0.83 | AVPR2 (0.49) | MEN1KMT2AAVPR2AVPR1AMAPT | |
| SCHEMBL8317560 | 0.81 | AVPR2 (0.43) | AVPR2AVPR1AALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL7333536 | 0.81 | AVPR1A (0.45) | AVPR2AVPR1ASMN1; SMN2 | |
| SCHEMBL7333302 | 0.80 | AVPR1A (0.50) | KMT2AAVPR2AVPR1ASMN1; SMN2 | |
| SCHEMBL7360343 | 0.79 | AVPR1A (0.44) | MEN1KMT2AAVPR2AVPR1AALDH1A1 | |
| SCHEMBL7333306 | 0.77 | AVPR2 (0.64) | AVPR2AVPR1A | |
| SCHEMBL7339753 | 0.76 | AVPR2 (0.57) | AVPR2AVPR1A | |
| SCHEMBL13497805 | 0.71 | KMT2A (0.61) | MEN1KMT2AALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636625-B1 | Tricyclic diazepines vasopressin and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1999-01-27 | — | — | EP | disclosed |