Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31472232 | 0.90 | — | — | |
| SCHEMBL8316025 | 0.79 | USP2 (0.36) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL9207799 | 0.77 | USP2 (0.33) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL9208041 | 0.72 | — | — | |
| SCHEMBL1129493 | 0.71 | USP2 (0.33) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL4023450 | 0.70 | NPSR1 (0.34) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL4874234 | 0.69 | ALDH1A1 (0.39) | USP2ALDH1A1LMNACYP1A2TSHR | |
| Cyclopentane SCHEMBL9063797 | 0.69 | ALDH1A1 (0.39) | USP2ALDH1A1LMNACYP1A2TSHR | |
| Cyclohexane SCHEMBL16390833 | 0.69 | ALDH1A1 (0.39) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL22444527 | 0.69 | ALDH1A1 (0.39) | USP2ALDH1A1LMNACYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562439-B1 | Triazolopyridazines as antioasthmatics | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-06-09 | — | — | EP | disclosed |
| EP-0562440-B1 | Imidazopyridazines as antiasthmatics | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5491145-A | ANTIASTHMA, ANTI-PLATELET ACTIVATING FACTOR BRONCHOCONSTRICTION-INHIBITING AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-02-13 | — | — | US | disclosed |
| US-5482939-A | ANTI-PLATELET ACTIVATING FACTOR ACTIVITIES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-01-09 | — | — | US | disclosed |
| US-5389633-A | ANTIASTHMATIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0562439-A1 | Triazolopyridazines as antioasthmatics | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| EP-0562440-A1 | Imidazopyridazines as antiasthmatics | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |