Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315815 | 1.00 | TUBB1 (0.43) | TUBB1RECQLKMT2AMEN1NPC1 | |
| SCHEMBL9694219 | 0.90 | ALDH1A1 (0.45) | TUBB1ALDH1A1SMN1; SMN2CYP1A2HPGD | |
| SCHEMBL9694216 | 0.90 | ALDH1A1 (0.45) | TUBB1ALDH1A1SMN1; SMN2CYP1A2HPGD | |
| Hydrochloric Acid SCHEMBL8316467 | 0.89 | ALDH1A1 (0.44) | TUBB1ALDH1A1SMN1; SMN2CYP1A2HPGD | |
| Hydrochloric Acid SCHEMBL8316464 | 0.89 | ALDH1A1 (0.44) | TUBB1ALDH1A1SMN1; SMN2CYP1A2HPGD | |
| SCHEMBL8313688 | 0.88 | TUBB1 (0.36) | TUBB1KMT2AMEN1NPC1POLB | |
| SCHEMBL8313691 | 0.88 | TUBB1 (0.36) | TUBB1KMT2AMEN1NPC1POLB | |
| SCHEMBL8315945 | 0.87 | APP (0.45) | TUBB1KMT2AMEN1ALDH1A1APP | |
| SCHEMBL8315946 | 0.87 | APP (0.45) | TUBB1KMT2AMEN1ALDH1A1APP | |
| Hydrochloric Acid SCHEMBL8317323 | 0.86 | APP (0.44) | TUBB1KMT2AMEN1ALDH1A1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0351856-B1 | Thiazolo[5,4-b]azepine compounds | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-09-15 | — | — | EP | disclosed |
| US-4956360-A | LIPOPEROXIDE INHIBITORS, ENZYME INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-09-11 | — | — | US | disclosed |