Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 16/20 | 0.72 |
| ▸ | PDE4B | Q07343 | 16/20 | 0.72 |
| ▸ | PDE4C | Q08493 | 16/20 | 0.72 |
| ▸ | PDE4D | Q08499 | 16/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4819738 | 0.89 | PDE4A (0.74) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL4819741 | 0.89 | PDE4A (0.74) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL8319617 | 0.88 | PDE4A (0.59) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL8319800 | 0.88 | PDE4A (0.77) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8320190 | 0.86 | PDE4A (0.62) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL8268706 | 0.85 | PDE4A (0.70) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8321041 | 0.85 | TUBB1 (0.64) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL4821508 | 0.84 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4821515 | 0.84 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8269865 | 0.82 | PDE4A (0.59) | PDE4APDE4BPDE4CPDE4DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078144-A2 | DIPHENYLETHYLENE COMPOUNDS AND USES THEREOF | CELGENE CORPORATION (US) | 2004-09-16 | — | — | WO | disclosed |