Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 17/20 | 0.59 |
| ▸ | PDE4B | Q07343 | 17/20 | 0.59 |
| ▸ | PDE4C | Q08493 | 17/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 17/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315838 | 0.88 | PDE4A (0.72) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL8319800 | 0.88 | PDE4A (0.77) | PDE4APDE4BPDE4CPDE4DNQO2 | |
| SCHEMBL8269865 | 0.85 | PDE4A (0.59) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL4816600 | 0.84 | PDE4A (0.80) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4816595 | 0.84 | PDE4A (0.80) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8319803 | 0.84 | PDE4A (0.80) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8268706 | 0.82 | PDE4A (0.70) | PDE4APDE4BPDE4CPDE4DNQO2 | |
| SCHEMBL8321025 | 0.82 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL13986032 | 0.81 | PDE4A (0.56) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8271316 | 0.80 | PDE4A (0.65) | PDE4APDE4BPDE4CPDE4DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078144-A2 | DIPHENYLETHYLENE COMPOUNDS AND USES THEREOF | CELGENE CORPORATION (US) | 2004-09-16 | — | — | WO | disclosed |