Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 6/20 | 0.40 |
| ▸ | AVPR1B | P47901 | 3/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | LDHB | P07195 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315058 | 0.88 | KMT2A (0.43) | AVPR1AAVPR2MEN1KMT2A | |
| SCHEMBL8317072 | 0.85 | AVPR1A (0.50) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL8313496 | 0.84 | KCNJ5 (0.45) | AVPR1AAVPR1BNAMPT | |
| SCHEMBL8316223 | 0.84 | GAA (0.46) | MEN1KMT2ALDHALDHB | |
| SCHEMBL7332706 | 0.83 | AVPR2 (0.47) | AVPR1AAVPR1BAVPR2MEN1KMT2A | |
| SCHEMBL8313872 | 0.82 | AVPR1A (0.48) | AVPR1AAVPR1BAVPR2MEN1KMT2A | |
| SCHEMBL8564664 | 0.80 | NAMPT (0.47) | AVPR1AAVPR1BAVPR2MEN1KMT2A | |
| SCHEMBL7331940 | 0.78 | AVPR2 (0.42) | AVPR1AAVPR2 | |
| SCHEMBL7333364 | 0.78 | AVPR1A (0.61) | AVPR1AAVPR2 | |
| SCHEMBL8314230 | 0.78 | AVPR1A (0.48) | AVPR1AAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636625-B1 | Tricyclic diazepines vasopressin and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1999-01-27 | — | — | EP | disclosed |