Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 5/20 | 0.50 |
| ▸ | APP | P05067 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696641 | 0.85 | F2RL3 (0.53) | F2RL3APPMAPTSMN1; SMN2KDM4E | |
| Bromide SCHEMBL8314377 | 0.80 | ESR1 (0.48) | F2RL3APPMAPTSMN1; SMN2KDM4E | |
| SCHEMBL8314988 | 0.78 | F2RL3 (0.41) | F2RL3MAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL8310999 | 0.78 | KDM4E (0.50) | F2RL3APPMAPTSMN1; SMN2KDM4E | |
| SCHEMBL8314504 | 0.76 | RAB9A (0.70) | F2RL3APPMAPTSMN1; SMN2KDM4E | |
| SCHEMBL12293318 | 0.74 | RAB9A (0.63) | MAPTSMN1; SMN2KDM4ENPC1ALDH1A1 | |
| SCHEMBL19625330 | 0.74 | CYP1A1 (0.69) | MAPTSMN1; SMN2KDM4ENPC1ALDH1A1 | |
| SCHEMBL19625326 | 0.74 | KMT2A (0.57) | MAPTSMN1; SMN2KDM4ENPC1ALDH1A1 | |
| SCHEMBL8312888 | 0.73 | MAPT (0.56) | APPMAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL10220288 | 0.72 | CYP19A1 (0.59) | MAPTSMN1; SMN2NPC1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528337-B1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-10-20 | — | — | EP | disclosed |
| US-5296495-A | Antiallergens, antiinflammatory | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0528337-A1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |