⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7414305 | 0.82 | — | — | |
| SCHEMBL8319116 | 0.81 | — | — | |
| SCHEMBL7844318 | 0.79 | — | — | |
| SCHEMBL7408863 | 0.78 | — | — | |
| SCHEMBL8314475 | 0.78 | PARP1 (0.46) | — | |
| Hydrochloric Acid SCHEMBL8105661 | 0.78 | — | — | |
| SCHEMBL7834788 | 0.78 | — | — | |
| SCHEMBL7415065 | 0.77 | — | — | |
| SCHEMBL7845046 | 0.77 | PARP1 (0.41) | — | |
| SCHEMBL7835924 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772615-B1 | IMIDAZO[1,2-a]INDENO[1,2-e]PYRAZINE-2-CARBOXYLIC ACID DERIVATIVES, PREPARATION THEREOF AND DRUGS CONTAINING SAME | RHONE POULENC RORER SA (FR) | 1999-09-22 | — | — | EP | disclosed |
| EP-0772615-A1 | IMIDAZO 1,2-a]INDENO 1,2-e]PYRAZINE-2-CARBOXYLIC ACID DERIVATIVES, PREPARATION THEREOF AND DRUGS CONTAINING SAME | Aventis Pharma S.A. (FR) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996002544-A1 | IMIDAZO[1,2-a]INDENO[1,2-e]PYRAZINE-2-CARBOXYLIC ACID DERIVATIVES, PREPARATION THEREOF AND DRUGS CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1996-02-01 | — | — | WO | disclosed |