Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416013 | 0.78 | — | — | |
| SCHEMBL8795893 | 0.71 | PARP1 (0.47) | PARP1 | |
| SCHEMBL8893399 | 0.64 | — | — | |
| SCHEMBL4068970 | 0.63 | PARP1 (1.00) | PARP1 | |
| SCHEMBL30049268 | 0.62 | TLR9 (0.79) | PARP1 | |
| SCHEMBL987760 | 0.62 | TLR9 (0.79) | PARP1 | |
| SCHEMBL7418792 | 0.60 | — | — | |
| SCHEMBL7411619 | 0.60 | — | — | |
| SCHEMBL3563285 | 0.58 | TDP2 (1.00) | PARP1 | |
| SCHEMBL16687099 | 0.58 | PTGS1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772615-B1 | IMIDAZO[1,2-a]INDENO[1,2-e]PYRAZINE-2-CARBOXYLIC ACID DERIVATIVES, PREPARATION THEREOF AND DRUGS CONTAINING SAME | RHONE POULENC RORER SA (FR) | 1999-09-22 | — | — | EP | disclosed |
| EP-0772615-A1 | IMIDAZO 1,2-a]INDENO 1,2-e]PYRAZINE-2-CARBOXYLIC ACID DERIVATIVES, PREPARATION THEREOF AND DRUGS CONTAINING SAME | Aventis Pharma S.A. (FR) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996002544-A1 | IMIDAZO[1,2-a]INDENO[1,2-e]PYRAZINE-2-CARBOXYLIC ACID DERIVATIVES, PREPARATION THEREOF AND DRUGS CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1996-02-01 | — | — | WO | disclosed |