Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9111109 | 1.00 | MAPT (0.47) | MAPTHTTBRD4ALDH1A1NTRK1 | |
| SCHEMBL9110706 | 0.85 | MAPT (0.65) | MAPTHTTALDH1A1KMT2ATXNRD1 | |
| SCHEMBL8313767 | 0.85 | MAPT (0.65) | MAPTHTTALDH1A1KMT2ATXNRD1 | |
| SCHEMBL13731224 | 0.85 | MAPT (0.49) | MAPTHTTALDH1A1KMT2ATXNRD1 | |
| SCHEMBL22770018 | 0.85 | MAPT (0.46) | MAPTHTTALDH1A1KMT2ATXNRD1 | |
| SCHEMBL13731227 | 0.85 | MAPT (0.49) | MAPTHTTALDH1A1KMT2ATXNRD1 | |
| SCHEMBL15472354 | 0.83 | MAPT (0.48) | MAPTHTTBRD4ALDH1A1KMT2A | |
| SCHEMBL15466529 | 0.82 | MAPT (0.55) | MAPTHTTALDH1A1KMT2A | |
| SCHEMBL13732751 | 0.82 | MAPT (0.55) | MAPTHTTALDH1A1KMT2A | |
| SCHEMBL16563740 | 0.78 | ALDH1A1 (0.61) | MAPTHTTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590428-B1 | Azaquinoxalines, process for their preparation, and their use | HOECHST AG (DE) | 1999-12-15 | — | — | EP | disclosed |
| US-5424311-A | A viricides for treating viral diseases; HIV enzyme inhibitor | HOESCHST AKTIENGESELLSCHAFT (DE) | 1995-06-13 | — | — | US | disclosed |
| EP-0590428-A1 | Azaquinoxalines, process for their preparation, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |