SCHEMBL8316671

SCHEMBL8316671

CCCON=C([C]=O)c1csc(N)n1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.46
ALDH1A1 P00352 5/20 0.46
RAB9A P51151 5/20 0.46
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
NPC1 O15118 4/20 0.46
ITGB1 P05556 1/20 0.35
ITGA4 P13612 1/20 0.35
LMNA P02545 2/20 0.34
MAPK1 P28482 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
SMN1; SMN2 Q16637 5/20 0.33
RECQL P46063 1/20 0.33
GABRA5 P31644 1/20 0.32
GABRB2 P47870 1/20 0.32
HSD17B10 Q99714 1/20 0.32
NOS1 P29475 1/20 0.31
POLB P06746 2/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9329855 1.00 MAPT (0.46) MAPTALDH1A1RAB9AMEN1KMT2A
SCHEMBL9363035 1.00 MAPT (0.46) MAPTALDH1A1RAB9AMEN1KMT2A
SCHEMBL9328934 0.92 MEN1 (0.44) MAPTALDH1A1RAB9AMEN1KMT2A
SCHEMBL9363888 0.92 MEN1 (0.44) MAPTALDH1A1RAB9AMEN1KMT2A
SCHEMBL8311583 0.92 MEN1 (0.44) MAPTALDH1A1RAB9AMEN1KMT2A
SCHEMBL9363536 0.91 MEN1 (0.43) MAPTALDH1A1RAB9AMEN1KMT2A
SCHEMBL9363540 0.91 MEN1 (0.43) MAPTALDH1A1RAB9AMEN1KMT2A
SCHEMBL9330069 0.90 MEN1 (0.42) MAPTALDH1A1RAB9AMEN1KMT2A
SCHEMBL9363025 0.90 MEN1 (0.42) MAPTALDH1A1RAB9AMEN1KMT2A
SCHEMBL8316834 0.89 MEN1 (0.51) MAPTALDH1A1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0093376-B2 1-Sulfo-2-azetidinone derivatives, their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1999-04-07 EP disclosed
EP-0280240-B1 Cephalosporin derivatives, process for their preparation and antibacterial agents BANYU PHARMA CO LTD (JP) 1994-09-14 EP disclosed
EP-0234549-B1 METHOD FOR PRODUCTION OF CEPHALOSPORIN COMPOUNDS Takeda Chemical Industries, Ltd. (JP) 1992-12-16 EP disclosed
US-5049665-A Cephalosporin derivatives BANYU PHARMACEUTICAL CO., LTD. (JP) 1991-09-17 US disclosed
US-4980464-A Method for production of cephalosporin compounds TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1990-12-25 US disclosed
US-4918070-A Antibiotics BANYU PHARMACEUTICAL CO., LTD. (JP) 1990-04-17 US disclosed
EP-0093376-B1 1-SULFO-2-AZETIDINONE DERIVATIVES, THEIR PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 1990-03-21 EP disclosed
US-4822788-A MICROBIOCIDES, BETA-LACTAMASE INHIBITORS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1989-04-18 US disclosed
US-4822790-A ANTIMICROBIOCIDES OR BETA-LACTAMASE INHIBITORS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1989-04-18 US disclosed
US-4801703-A PHOSPHORUS COMPOUNDS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1989-01-31 US disclosed
EP-0135683-A1 Method for production of cephalosporin compounds Takeda Chemical Industries, Ltd. (JP) 1985-04-03 EP disclosed
EP-0135194-A1 Azetidinones and their production Takeda Chemical Industries, Ltd. (JP) 1985-03-27 EP disclosed
EP-0126859-A1 Intermediate compounds for preparing cephem compounds and processes for their preparation FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-12-05 EP disclosed
EP-0093376-A2 1-Sulfo-2-azetidinone derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1983-11-09 EP disclosed
US-4405617-A ANTIBIOTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-09-20 US disclosed
EP-0074611-A2 Method for production of cephalosporin compounds Takeda Chemical Industries, Ltd. (JP) 1983-03-23 EP disclosed
US-4350694-A OXACEPHALOSPORINS/; FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1982-09-21 US disclosed
EP-0053816-A1 1-Sulfo-2-oxoazetidine derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1982-06-16 EP disclosed
EP-0033965-A2 New cephem compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-08-19 EP disclosed
US-4234724-A OXADETHIACEPHEMCARBOXYLIC ACIDS FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) 1980-11-18 US disclosed