Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9332012 | 1.00 | MEN1 (0.51) | MEN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL8316832 | 1.00 | MEN1 (0.51) | MEN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL9329025 | 0.89 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL9329855 | 0.89 | MAPT (0.46) | MEN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL8316671 | 0.89 | MAPT (0.46) | MEN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL9363035 | 0.89 | MAPT (0.46) | MEN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL9329412 | 0.88 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL9781980 | 0.87 | MEN1 (0.54) | MEN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL9330056 | 0.87 | MEN1 (0.54) | MEN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL9781974 | 0.87 | MEN1 (0.54) | MEN1KMT2AALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363223-A2 | 3-Aryloxymethyl-cephalosporin derivatives, their preparation and their medical use | Sankyo Company Limited (JP) | 1990-04-11 | — | — | EP | claimed |
| EP-0093376-B2 | 1-Sulfo-2-azetidinone derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-04-07 | — | — | EP | disclosed |
| US-5389626-A | 3-aryloxmethyl-cephalosporin derivatives, and their medical use | SANKYO COMPANY, LIMITED (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0280240-B1 | Cephalosporin derivatives, process for their preparation and antibacterial agents | BANYU PHARMA CO LTD (JP) | 1994-09-14 | — | — | EP | disclosed |
| EP-0234549-B1 | METHOD FOR PRODUCTION OF CEPHALOSPORIN COMPOUNDS | Takeda Chemical Industries, Ltd. (JP) | 1992-12-16 | — | — | EP | disclosed |
| US-5049665-A | Cephalosporin derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-09-17 | — | — | US | disclosed |
| US-4918070-A | Antibiotics | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1990-04-17 | — | — | US | disclosed |
| EP-0363223-A2 | 3-Aryloxymethyl-cephalosporin derivatives, their preparation and their medical use | Sankyo Company Limited (JP) | 1990-04-11 | — | — | EP | disclosed |
| EP-0093376-B1 | 1-SULFO-2-AZETIDINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1990-03-21 | — | — | EP | disclosed |
| US-4822790-A | ANTIMICROBIOCIDES OR BETA-LACTAMASE INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0135683-A1 | Method for production of cephalosporin compounds | Takeda Chemical Industries, Ltd. (JP) | 1985-04-03 | — | — | EP | disclosed |
| EP-0135194-A1 | Azetidinones and their production | Takeda Chemical Industries, Ltd. (JP) | 1985-03-27 | — | — | EP | disclosed |
| EP-0126859-A1 | Intermediate compounds for preparing cephem compounds and processes for their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-12-05 | — | — | EP | disclosed |
| EP-0093376-A2 | 1-Sulfo-2-azetidinone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1983-11-09 | — | — | EP | disclosed |
| US-4405617-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-09-20 | — | — | US | disclosed |
| EP-0074611-A2 | Method for production of cephalosporin compounds | Takeda Chemical Industries, Ltd. (JP) | 1983-03-23 | — | — | EP | disclosed |
| US-4350694-A | OXACEPHALOSPORINS/; | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-09-21 | — | — | US | disclosed |
| EP-0053816-A1 | 1-Sulfo-2-oxoazetidine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1982-06-16 | — | — | EP | disclosed |
| EP-0033965-A2 | New cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-08-19 | — | — | EP | disclosed |
| US-4234724-A | OXADETHIACEPHEMCARBOXYLIC ACIDS | FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1980-11-18 | — | — | US | disclosed |