Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | EDNRB | P24530 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | MELK | Q14680 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204235 | 0.78 | EDNRB (0.46) | KDM4EALDH1A1SMN1; SMN2NPSR1LMNA | |
| SCHEMBL1027211 | 0.77 | AOC3 (0.43) | AOC3KDM4EALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL6341931 | 0.77 | AOC3 (0.43) | AOC3KDM4EALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL25082789 | 0.76 | AOC3 (0.42) | AOC3KDM4EALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL10446374 | 0.76 | AOC3 (0.42) | AOC3KDM4EALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL25082792 | 0.76 | HTT (0.44) | AOC3KDM4EALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL1854649 | 0.75 | AOC3 (0.46) | XDHSLC22A12AOC3KDM4EALDH1A1 | |
| SCHEMBL13516155 | 0.73 | ALDH1A1 (0.46) | AOC3KDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL17159798 | 0.72 | ALDH1A1 (0.41) | AOC3KDM4EALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL16793055 | 0.71 | AOC3 (0.46) | AOC3KDM4EALDH1A1NPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900223-A1 | THIENOPYRIDINE DERIVATIVES AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997040050-A1 | THIENOPYRIDINE DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |