SCHEMBL8317048

SCHEMBL8317048

O=C(O)[C@H]1O[C@H](O)CS1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8806821 1.00
SCHEMBL8806439 1.00
SCHEMBL8317054 1.00
SCHEMBL17683594 0.76
SCHEMBL7868218 0.74
SCHEMBL8874188 0.74
SCHEMBL13051904 0.74
SCHEMBL12996745 0.74 PPM1B (0.35)
SCHEMBL27869449 0.71
SCHEMBL6313676 0.70 PPM1B (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5693787-A Intermediates in the synthesis of 1,3-oxathiolanyl cytosine nucleoside analogues BIOCHEM PHARMA INC. (CA) 1997-12-02 US claimed
EP-0515157-B1 Processes for the diastereoselective synthesis of nucleosides IAF BIOCHEM INT (CA) 1997-09-03 EP claimed
WO-1992020669-A1 PROCESSES FOR THE DIASTEREOSELECTIVE SYNTHESIS OF NUCLEOSIDES BIOCHEM PHARMA INC. (CA) 1992-11-26 WO claimed
EP-0515157-A1 Processes for the diastereoselective synthesis of nucleosides BIOCHEM PHARMA INC. (CA) 1992-11-25 EP claimed
EP-0654031-B1 STEREOSELECTIVE SYNTHESIS OF NUCLEOSIDE ANALOGUES USING BICYCLIC INTERMEDIATE IAF BIOCHEM INT (CA) 1999-12-29 EP disclosed
US-5763606-A Stereoselective synthesis of nucleoside analogues using bicyclic intermediate BIOCHEM PHARMA, INC. (CA) 1998-06-09 US disclosed
US-5696254-A Processes for the diastereoselective synthesis of nucleoside analogues BIOCHEM PHARMA INC. (CA) 1997-12-09 US disclosed
US-5693787-A Intermediates in the synthesis of 1,3-oxathiolanyl cytosine nucleoside analogues BIOCHEM PHARMA INC. (CA) 1997-12-02 US disclosed
EP-0515157-B1 Processes for the diastereoselective synthesis of nucleosides IAF BIOCHEM INT (CA) 1997-09-03 EP disclosed
US-5663320-A Processes for the diastereoselective separation of nucleoside analogue synthetic intermediates BIOCHEM PHARMA, INC. (CA) 1997-09-02 US disclosed
WO-1992020669-A1 PROCESSES FOR THE DIASTEREOSELECTIVE SYNTHESIS OF NUCLEOSIDES BIOCHEM PHARMA INC. (CA) 1992-11-26 WO disclosed
EP-0515157-A1 Processes for the diastereoselective synthesis of nucleosides BIOCHEM PHARMA INC. (CA) 1992-11-25 EP disclosed