Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317237 | 0.66 | OPRM1 (0.34) | OPRM1 | |
| SCHEMBL8317231 | 0.64 | OPRM1 (0.34) | OPRM1 | |
| SCHEMBL20995941 | 0.61 | SMN1; SMN2 (0.40) | OPRM1 | |
| SCHEMBL8317848 | 0.60 | CHRM1 (0.56) | — | |
| SCHEMBL6913063 | 0.60 | CA12 (0.40) | OPRM1 | |
| SCHEMBL6913059 | 0.60 | CA12 (0.40) | OPRM1 | |
| SCHEMBL8317844 | 0.60 | CHRM1 (0.56) | — | |
| SCHEMBL20073128 | 0.60 | OPRM1 (0.45) | OPRM1 | |
| SCHEMBL3179314 | 0.57 | CYP1A2 (0.41) | OPRM1 | |
| SCHEMBL14017758 | 0.55 | SMN1; SMN2 (0.35) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998434-A | Composition for treating pain | ELI LILLY AND COMPANY (US) | 1999-12-07 | — | — | US | claimed |
| EP-0874828-A4 | COMPOSITION FOR TREATING PAIN | LILLY CO ELI (US) | 1999-09-01 | — | — | EP | claimed |
| EP-0874828-A1 | COMPOSITION FOR TREATING PAIN | ELI LILLY AND COMPANY (US) | 1998-11-04 | — | — | EP | claimed |
| WO-1997020819-A1 | COMPOSITION FOR TREATING PAIN | ELI LILLY AND COMPANY (US) | 1997-06-12 | — | — | WO | claimed |
| US-5998434-A | Composition for treating pain | ELI LILLY AND COMPANY (US) | 1999-12-07 | — | — | US | disclosed |