Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11455772 | 0.85 | CSNK2A1 (0.43) | CSNK2A1GAAMAPTTSHRPDE4B | |
| SCHEMBL7167776 | 0.82 | CSNK2A1 (0.41) | CSNK2A1PDE4BALDH1A1POLBHPGD | |
| SCHEMBL16695147 | 0.82 | LMNA (0.43) | CSNK2A1MAPTSMN1; SMN2TSHRPDE4B | |
| SCHEMBL17453392 | 0.81 | CSNK2A1 (0.40) | CSNK2A1PDE4BALDH1A1POLBHPGD | |
| SCHEMBL11463272 | 0.80 | HPGD (0.44) | CSNK2A1MAPTSMN1; SMN2PDE4BALDH1A1 | |
| SCHEMBL5330768 | 0.80 | MRGPRX4 (0.43) | CSNK2A1TSHR | |
| SCHEMBL11453034 | 0.80 | CSNK2A1 (0.36) | CSNK2A1DHFRMAPTPDE4BALDH1A1 | |
| SCHEMBL3362970 | 0.79 | PDE4B (0.42) | CSNK2A1PDE4BALDH1A1HPGDPTPN1 | |
| SCHEMBL12429188 | 0.78 | SLC6A4 (0.44) | CSNK2A1MAPTALDH1A1 | |
| SCHEMBL13349984 | 0.78 | CSNK2A1 (0.64) | CSNK2A1CYP3A4TSHRPDE4BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690050-B1 | (Thia)cycloalkyl(b) indole derivatives as 5-lipoxygenase inhibitors | ADIR (FR) | 1999-11-17 | — | — | EP | disclosed |
| US-5635516-A | SIDE EFFECT REDUCTION | ADIR ET COMPAGNIE (FR) | 1997-06-03 | — | — | US | disclosed |
| EP-0690050-A1 | (Thia)cycloalkyl(b) indole derivatives as 5-lipoxygenase inhibitors | ADIR ET COMPAGNIE (FR) | 1996-01-03 | — | — | EP | disclosed |