Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 3/20 | 0.51 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6991476 | 0.88 | MAOB (0.51) | CASRAOC3MAOBALDH1A1CYP3A4 | |
| SCHEMBL5990929 | 0.85 | CASR (0.50) | CASRAOC3ACHEL3MBTL1ALDH1A1 | |
| SCHEMBL14060408 | 0.85 | CASR (0.50) | CASRAOC3ACHEL3MBTL1ALDH1A1 | |
| SCHEMBL8081764 | 0.85 | MEN1 (0.49) | CASRAOC3L3MBTL1MAOBMTNR1A | |
| SCHEMBL27898376 | 0.83 | AOC3 (0.51) | CASRAOC3ACHEL3MBTL1ALDH1A1 | |
| SCHEMBL1254356 | 0.83 | AOC3 (0.56) | CASRAOC3ACHEL3MBTL1ALDH1A1 | |
| SCHEMBL952823 | 0.82 | CASR (0.51) | CASRAOC3ACHEL3MBTL1MAOB | |
| SCHEMBL16952756 | 0.82 | CHRM2 (0.48) | CASRAOC3ACHEL3MBTL1ALDH1A1 | |
| SCHEMBL3080355 | 0.82 | AOC3 (0.50) | CASRAOC3ACHEL3MBTL1CA1 | |
| SCHEMBL1050770 | 0.81 | CASR (0.54) | CASRAOC3ACHEL3MBTL1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102381916-B | Synthesis method of beta, beta-diaryl alkene | UNIV ZHEJIANG | 2014-03-12 | — | — | CN | disclosed |
| EP-0934940-A1 | CYTOKINE PRODUCTION INHIBITORS, TRIAZEPINE COMPOUNDS, AND INTERMEDIATES THEREOF | Japan Tobacco Inc. (JP) | 1999-08-11 | — | — | EP | disclosed |
| US-5807850-A | Therapeutic agent for osteoporosis and triazepine compound | JAPAN TOBACCO, INC. (JP) | 1998-09-15 | — | — | US | disclosed |
| EP-0792880-A1 | OSTEOPOROSIS REMEDY AND TRIAZEPINE COMPOUND | Japan Tobacco Inc. (JP) | 1997-09-03 | — | — | EP | disclosed |