Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 3/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14060408 | 1.00 | CASR (0.50) | CASRAOC3ACHEL3MBTL1TAAR1 | |
| SCHEMBL8317373 | 0.85 | CASR (0.51) | CASRAOC3ACHEL3MBTL1CA1 | |
| SCHEMBL10290007 | 0.83 | CASR (0.53) | CASRAOC3ACHEL3MBTL1TAAR1 | |
| SCHEMBL84440 | 0.83 | HDAC4 (0.55) | CASRAOC3ACHEL3MBTL1TAAR1 | |
| SCHEMBL11619720 | 0.83 | CASR (0.53) | CASRAOC3ACHEL3MBTL1TAAR1 | |
| SCHEMBL30601580 | 0.83 | HDAC4 (0.55) | CASRAOC3ACHEL3MBTL1TAAR1 | |
| SCHEMBL1254356 | 0.82 | AOC3 (0.56) | CASRAOC3ACHEL3MBTL1CA1 | |
| SCHEMBL27898376 | 0.82 | AOC3 (0.51) | CASRAOC3ACHEL3MBTL1TAAR1 | |
| SCHEMBL10446047 | 0.81 | AOC3 (0.53) | CASRAOC3ACHEL3MBTL1TAAR1 | |
| SCHEMBL15271036 | 0.81 | CASR (0.51) | CASRAOC3ACHEL3MBTL1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060287378-A1 | Novel pyrroles and imidazoles | WARNER-LAMBERT COMPANY LLC | 2006-12-21 | — | — | US | disclosed |
| US-20050239857-A1 | Novel imidazoles | BOLTON GARY L | 2005-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060287378-A1 | Novel pyrroles and imidazoles | PPIP5K2, PPIE, PPOX | CASR 4853/4885AOC3 1964/4885ACHE 1373/4885 |
| US-20050239857-A1 | Novel imidazoles | HMGCR, HMGB2, HMGB3 | CASR 4877/4885AOC3 1448/4885ACHE 1215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.