Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 4/20 | 0.52 |
| ▸ | CNR2 | P34972 | 10/20 | 0.47 |
| ▸ | CNR1 | P21554 | 5/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27335551 | 0.84 | CNR2 (0.55) | ICMTCNR2CNR1THRBKDM4C | |
| SCHEMBL3242119 | 0.78 | PTGDR2 (0.48) | THRBTP53GAA | |
| SCHEMBL9416407 | 0.78 | CNR2 (0.46) | CNR2CNR1GAA | |
| SCHEMBL4494230 | 0.78 | CNR2 (0.61) | ICMTCNR2CNR1KDM4CHRH2 | |
| SCHEMBL26630665 | 0.77 | KDM4C (0.58) | ICMTCNR2CNR1THRBKDM4C | |
| SCHEMBL3237092 | 0.76 | GAA (0.50) | THRBTP53GAA | |
| SCHEMBL3245321 | 0.76 | CNR2 (0.45) | CNR2CNR1TP53 | |
| SCHEMBL3230362 | 0.75 | AKR1B1 (0.43) | THRBTP53 | |
| SCHEMBL3245353 | 0.73 | CNR2 (0.41) | CNR2THRBTP53GAA | |
| SCHEMBL3241690 | 0.73 | THRB (0.40) | CNR2THRBTP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944385-A2 | USE OF 7-(1-AMINOMETHYL-2-OXA-7-AZA-BICYCLO 3.3.0]OCT-7-YL)-QUINOLONE CARBOXYLIC ACID AND NAPHTHYRIDONE CARBOXYLIC ACID DERIVATIVES FOR TREATING $i(HELICOBACTER PYLORI) INFECTIONS AND THE GASTRODUODENAL DISEASES ASSOCIATED THEREWITH | BAYER AG (DE) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998026768-A2 | USE OF 7-(1-AMINOMETHYL-2-OXA-7-AZA-BICYCLO[3.3.0]OCT-7-YL)-QUINOLONE CARBOXYLIC ACID AND NAPHTHYRIDONE CARBOXYLIC ACID DERIVATIVES FOR TREATING HELICOBACTER PYLORI INFECTIONS AND THE GASTRODUODENAL DISEASES ASSOCIATED THEREWITH | BAYER AKTIENGESELLSCHAFT (DE) | 1998-06-25 | — | — | WO | disclosed |