Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.36 |
| ▸ | RELA | Q04206 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KCNQ4 | P56696 | 2/20 | 0.34 |
| ▸ | KCNQ5 | Q9NR82 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8314473 | 0.77 | CYP4F2 (0.56) | CYP4F2CYP4A11TDP1CTDSP1NFKB1 | |
| SCHEMBL8313320 | 0.77 | POLB (0.34) | ALDH1A1TSHRNFKB1NFKB2RELA | |
| SCHEMBL6083239 | 0.77 | POLB (0.34) | ALDH1A1TSHRNFKB1NFKB2RELA | |
| SCHEMBL6081924 | 0.77 | POLB (0.34) | ALDH1A1TSHRNFKB1NFKB2RELA | |
| SCHEMBL6081926 | 0.76 | ELANE (0.32) | — | |
| SCHEMBL8318115 | 0.76 | ELANE (0.32) | — | |
| SCHEMBL6083248 | 0.76 | ELANE (0.32) | — | |
| SCHEMBL8313324 | 0.74 | ELANE (0.33) | — | |
| SCHEMBL27396218 | 0.73 | ELANE (0.37) | HPGDCYP1A2CYP2C19 | |
| SCHEMBL3102874 | 0.72 | CYSLTR2 (0.42) | TDP1CTDSP1ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771801-B1 | Chromane derivatives | AMERICAN HOME PROD (US) | 1999-03-03 | — | — | EP | disclosed |
| US-5750556-A | REDUCING DOPAMINE SYNTHESIS AND RELEASE, SCHIZOPHRENIA | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-05-12 | — | — | US | disclosed |
| EP-0771801-A1 | Chromane derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-05-07 | — | — | EP | disclosed |