Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 10/20 | 0.62 |
| ▸ | CCND1 | P24385 | 10/20 | 0.62 |
| ▸ | PRKCQ | Q04759 | 6/20 | 0.59 |
| ▸ | PRKD3 | O94806 | 5/20 | 0.59 |
| ▸ | PRKCG | P05129 | 5/20 | 0.59 |
| ▸ | PRKCB | P05771 | 5/20 | 0.59 |
| ▸ | PRKCA | P17252 | 5/20 | 0.59 |
| ▸ | PRKCH | P24723 | 5/20 | 0.59 |
| ▸ | PRKCI | P41743 | 5/20 | 0.59 |
| ▸ | PRKCE | Q02156 | 5/20 | 0.59 |
| ▸ | PRKCZ | Q05513 | 5/20 | 0.59 |
| ▸ | PRKCD | Q05655 | 5/20 | 0.59 |
| ▸ | PRKD1 | Q15139 | 5/20 | 0.59 |
| ▸ | CCNE2 | O96020 | 5/20 | 0.55 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.55 |
| ▸ | CDK2 | P24941 | 5/20 | 0.55 |
| ▸ | PRKACA | P17612 | 3/20 | 0.52 |
| ▸ | PRKACG | P22612 | 3/20 | 0.52 |
| ▸ | PRKACB | P22694 | 3/20 | 0.52 |
| ▸ | CAMK2B | Q13554 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22401390 | 0.89 | CDK4 (0.47) | CDK4CCND1PRKCQPRKD3PRKCG | |
| SCHEMBL23875844 | 0.79 | CHRM2 (0.40) | CDK4CCND1PRKCQPRKD3PRKCG | |
| SCHEMBL17897787 | 0.78 | CHRM2 (0.41) | CDK4CCND1CCNB2CDK1MAPT | |
| SCHEMBL8121576 | 0.77 | CDK4 (1.00) | CDK4CCND1PRKCQPRKD3PRKCG | |
| SCHEMBL14459877 | 0.75 | ROCK2 (0.51) | CDK4CCND1PRKCQPRKD3PRKCG | |
| SCHEMBL14459624 | 0.75 | ROCK2 (0.51) | CDK4CCND1PRKCQPRKD3PRKCG | |
| SCHEMBL8316417 | 0.74 | PRKD3 (1.00) | CDK4CCND1PRKCQPRKD3PRKCG | |
| SCHEMBL13075769 | 0.74 | CDK4 (0.79) | CDK4CCND1PRKCQPRKD3PRKCG | |
| SCHEMBL14396755 | 0.72 | CHRM2 (0.44) | PRKCGPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL8120443 | 0.72 | CDK4 (0.74) | CDK4CCND1PRKCQPRKD3PRKCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630242-B1 | FURTHER INDOLE DERIVATIVES WITH ANTIVIRAL ACTIVITY | WELLCOME FOUND (GB) | 1999-01-20 | — | — | EP | claimed |