Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGK1 | O00141 | 4/20 | 0.74 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.67 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.67 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.67 |
| ▸ | CAMKK2 | Q96RR4 | 3/20 | 0.61 |
| ▸ | AXL | P30530 | 5/20 | 0.60 |
| ▸ | CLK1 | P49759 | 2/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.56 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.56 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.56 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.55 |
| ▸ | MAP3K11 | Q16584 | 4/20 | 0.54 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.53 |
| ▸ | CDK8 | P49336 | 1/20 | 0.51 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8320085 | 0.89 | AXL (0.76) | SGK1MAPK8MAPK9MAPK10CAMKK2 | |
| SCHEMBL8320015 | 0.88 | MAPK8 (0.65) | SGK1MAPK8MAPK9MAPK10CAMKK2 | |
| SCHEMBL8320560 | 0.88 | MAP3K11 (0.69) | SGK1MAPK8MAPK9MAPK10CAMKK2 | |
| SCHEMBL8320557 | 0.87 | MAPK8 (0.70) | SGK1MAPK8MAPK9MAPK10CAMKK2 | |
| SCHEMBL8322707 | 0.85 | MAPK8 (0.61) | SGK1MAPK8MAPK9MAPK10CAMKK2 | |
| SCHEMBL8314581 | 0.85 | SGK1 (0.62) | SGK1MAPK8MAPK9MAPK10CAMKK2 | |
| SCHEMBL8941736 | 0.85 | SGK1 (1.00) | SGK1MAPK8MAPK9CAMKK2AXL | |
| SCHEMBL8320314 | 0.84 | MAPK8 (0.59) | SGK1MAPK8MAPK9MAPK10CAMKK2 | |
| SCHEMBL14049065 | 0.84 | DYRK1A (0.79) | MAPK8MAPK9MAPK10AXLCLK1 | |
| SCHEMBL13745344 | 0.83 | MAPK8 (0.58) | SGK1MAPK8MAPK9MAPK10CAMKK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078756-A2 | JNK INHIBITORS | EISAI CO., LTD. (JP) | 2004-09-16 | — | — | WO | disclosed |