Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339252 | 0.91 | AVPR2 (0.49) | AVPR2MAPTAVPR1A | |
| SCHEMBL8315803 | 0.85 | AVPR2 (0.46) | AVPR2MAPTHTTNPC1LMNA | |
| SCHEMBL7340153 | 0.84 | AVPR1A (0.43) | AVPR2L3MBTL1SMN1; SMN2MAPTLMNA | |
| SCHEMBL8628737 | 0.81 | MEN1 (0.45) | AVPR2L3MBTL1SMN1; SMN2MAPTAVPR1A | |
| SCHEMBL7333536 | 0.80 | AVPR1A (0.45) | AVPR2SMN1; SMN2NPC1AVPR1APOLB | |
| SCHEMBL7333302 | 0.78 | AVPR1A (0.50) | AVPR2SMN1; SMN2HTTNPC1LMNA | |
| SCHEMBL8316248 | 0.78 | AVPR2 (0.58) | AVPR2AVPR1A | |
| SCHEMBL27405027 | 0.77 | AVPR2 (0.61) | AVPR2MAPTHTTNPC1LMNA | |
| SCHEMBL7332088 | 0.77 | AVPR2 (0.50) | AVPR2MAPTAVPR1A | |
| SCHEMBL7339596 | 0.74 | AVPR2 (0.49) | AVPR2MAPTHTTNPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636625-B1 | Tricyclic diazepines vasopressin and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1999-01-27 | — | — | EP | disclosed |