Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7957798 | 0.77 | ALDH1A1 (0.43) | NT5EALDH1A1MAPTTDP1 | |
| SCHEMBL7955544 | 0.71 | NT5E (0.47) | NT5EALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL2943984 | 0.70 | CA12 (0.48) | ALDH1A1KDM4ELMNA | |
| SCHEMBL2543592 | 0.70 | CA12 (0.48) | ALDH1A1KDM4ELMNA | |
| SCHEMBL15781205 | 0.70 | CA12 (0.48) | ALDH1A1KDM4ELMNA | |
| SCHEMBL4609138 | 0.70 | CA12 (0.48) | ALDH1A1KDM4ELMNA | |
| SCHEMBL7596584 | 0.70 | CA12 (0.48) | ALDH1A1KDM4ELMNA | |
| SCHEMBL9053183 | 0.70 | CA12 (0.48) | ALDH1A1KDM4ELMNA | |
| SCHEMBL15782553 | 0.70 | CA12 (0.48) | ALDH1A1KDM4ELMNA | |
| SCHEMBL2296345 | 0.70 | CA12 (0.48) | ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819135-B1 | SUGAR-MODIFIED CYTOSTATICS | BAYER AG (DE) | 1999-11-17 | — | — | EP | disclosed |