Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 1.00 |
| ▸ | CTSD | P07339 | 16/20 | 1.00 |
| ▸ | BACE2 | Q9Y5Z0 | 16/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8322861 | 0.90 | CTSD (1.00) | BACE1CTSDBACE2 | |
| SCHEMBL5928250 | 0.85 | BACE1 (0.74) | BACE1CTSDBACE2 | |
| SCHEMBL5928463 | 0.80 | BACE1 (0.73) | BACE1CTSDBACE2 | |
| SCHEMBL5928260 | 0.80 | CTSD (0.87) | BACE1CTSDBACE2 | |
| SCHEMBL5928259 | 0.80 | CTSD (0.87) | BACE1CTSDBACE2 | |
| SCHEMBL5344469 | 0.80 | BACE1 (0.91) | BACE1CTSDBACE2 | |
| SCHEMBL5352154 | 0.80 | BACE1 (0.91) | BACE1CTSDBACE2 | |
| SCHEMBL5928269 | 0.78 | BACE1 (0.63) | BACE1CTSDBACE2 | |
| SCHEMBL21527047 | 0.76 | BACE1 (1.00) | BACE1CTSDBACE2 | |
| SCHEMBL20899826 | 0.76 | BACE1 (1.00) | BACE1CTSDBACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004080376-A2 | HYDROXYETHYLAMINE COMPOUNDS HAVING ASP2 INHIBITORY ACTIVITY FOR THE TREATMENT OF ALZHEIMER’S DISEASE | GLAXO GROUP LIMITED (GB) | 2004-09-23 | — | — | WO | disclosed |