Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 4/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.42 |
| ▸ | CYP24A1 | Q07973 | 8/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.38 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.38 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8319550 | 0.90 | PRMT5 (0.42) | PRMT5WDR77CYP24A1HDAC6CYP17A1 | |
| SCHEMBL8319561 | 0.88 | CYP24A1 (0.41) | PRMT5WDR77CYP24A1HDAC6 | |
| SCHEMBL8319557 | 0.88 | CYP24A1 (0.42) | PRMT5WDR77CYP24A1HDAC6 | |
| SCHEMBL8314351 | 0.87 | PRMT5 (0.49) | PRMT5WDR77ITGB3ITGA2BHDAC6 | |
| SCHEMBL8457084 | 0.83 | PRMT5 (0.45) | PRMT5WDR77ITGB3ITGA2BHDAC6 | |
| SCHEMBL8315226 | 0.82 | ITGB3 (0.61) | CYP24A1ITGB3ITGA2BCYP26A1CYP3A4 | |
| SCHEMBL8455279 | 0.80 | ITGB3 (0.60) | PRMT5WDR77ITGB3ITGA2BHDAC6 | |
| SCHEMBL8558144 | 0.80 | ITGB3 (0.45) | PRMT5WDR77ITGB3ITGA2BHDAC6 | |
| Trifluoroacetic Acid SCHEMBL8320411 | 0.79 | ITGB3 (0.56) | CYP24A1ITGB3ITGA2BTPSAB1TPSD1 | |
| SCHEMBL8560838 | 0.79 | PRMT5 (0.46) | PRMT5WDR77ITGB3ITGA2BHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0897920-A1 | NOVEL HETEROCYCLIC COMPOUNDS HAVING PLATELET AGGREGATION INHIBITORY EFFECTS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1999-02-24 | — | — | EP | disclosed |