Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8318718 | 0.96 | GAA (0.39) | CYP4F2CYP4A11GAAMGAMSI | |
| SCHEMBL8319516 | 0.90 | GAA (0.41) | CYP4F2CYP4A11GAAMGAMSI | |
| Hydrochloric Acid SCHEMBL27032540 | 0.81 | CYP4F2 (0.47) | CYP4F2CYP4A11HSD17B10CYP4Z1CA12 | |
| SCHEMBL689345 | 0.81 | CYP4F2 (0.47) | CYP4F2CYP4A11HSD17B10CYP4Z1CA12 | |
| SCHEMBL4476235 | 0.75 | GAA (0.61) | GAAMGAMSIMGAM2HSD17B10 | |
| SCHEMBL6303688 | 0.75 | GAA (0.61) | GAAMGAMSIMGAM2HSD17B10 | |
| SCHEMBL11215907 | 0.74 | PAOX (0.38) | TSHRALDH1A1CYP1A2SMN1; SMN2MAPK1 | |
| SCHEMBL689390 | 0.74 | CA12 (0.57) | GAAMGAMSIMGAM2HSD17B10 | |
| SCHEMBL6138808 | 0.73 | GAA (0.58) | CYP4F2CYP4A11GAAMGAMSI | |
| SCHEMBL5193775 | 0.72 | GAA (0.52) | GAAMGAMSIMGAM2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900223-A1 | THIENOPYRIDINE DERIVATIVES AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997040050-A1 | THIENOPYRIDINE DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |