Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.37 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11211920 | 0.93 | PDE3B (0.36) | PAOXPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9021719 | 0.84 | TBXAS1 (0.53) | TBXAS1RXFP1LMNATSHRNFKB1 | |
| SCHEMBL25754946 | 0.82 | TBXAS1 (0.41) | TBXAS1PDE3BPDE3AP2RY12HRH3 | |
| SCHEMBL26108897 | 0.81 | L3MBTL1 (0.41) | ALDH1A1LMNA | |
| SCHEMBL26111368 | 0.81 | L3MBTL1 (0.41) | ALDH1A1LMNA | |
| SCHEMBL26106860 | 0.81 | L3MBTL1 (0.41) | ALDH1A1LMNA | |
| SCHEMBL26109555 | 0.81 | L3MBTL1 (0.41) | ALDH1A1LMNA | |
| SCHEMBL26111664 | 0.81 | L3MBTL1 (0.41) | ALDH1A1LMNA | |
| SCHEMBL26111608 | 0.81 | L3MBTL1 (0.41) | ALDH1A1LMNA | |
| SCHEMBL26110441 | 0.81 | L3MBTL1 (0.41) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0024538-B1 | 1,2,4-TRIAZOLYL-ENOL ETHERS, PROCESS FOR PREPARING THEM AND THEIR USE AS FUNGICIDES | BAYER AG (DE) | 1983-01-26 | — | — | EP | claimed |