Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.64 |
| ▸ | DRD3 | P35462 | 10/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 4/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | BACE1 | P56817 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8690452 | 0.99 | DRD2 (0.62) | DRD2DRD3MEN1KMT2ADRD4 | |
| Hydrochloric Acid SCHEMBL8904391 | 0.99 | DRD2 (0.62) | DRD2DRD3MEN1KMT2ADRD4 | |
| SCHEMBL8383040 | 0.84 | KDM4E (0.45) | DRD2DRD3BCHEACHEKDM4E | |
| SCHEMBL8313826 | 0.83 | DRD2 (0.67) | DRD2DRD3 | |
| SCHEMBL8316979 | 0.83 | DRD2 (0.67) | DRD2DRD3 | |
| SCHEMBL6215646 | 0.82 | DRD2 (0.65) | DRD2DRD3MEN1KMT2ADRD4 | |
| SCHEMBL8317409 | 0.82 | DRD2 (0.65) | DRD2DRD3MEN1KMT2ADRD4 | |
| SCHEMBL6215644 | 0.82 | DRD2 (0.65) | DRD2DRD3MEN1KMT2ADRD4 | |
| SCHEMBL8318986 | 0.82 | DRD2 (0.65) | DRD2DRD3MEN1KMT2ADRD4 | |
| SCHEMBL8385743 | 0.82 | KDM4E (0.46) | DRD2DRD3BCHEACHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691342-B1 | Benzopyran derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-04-28 | — | — | EP | disclosed |
| EP-0691342-A1 | Benzopyrane derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-01-10 | — | — | EP | disclosed |