Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALPG | P10696 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6597474 | 0.84 | KMT2A (0.38) | KMT2ACCR1ALDH1A1LMNAALPG | |
| SCHEMBL10468320 | 0.73 | KMT2A (0.43) | KMT2ACCR1ALDH1A1LMNAALPG | |
| SCHEMBL11861977 | 0.70 | CCR1 (0.44) | KMT2ACCR1ALDH1A1LMNAALPG | |
| SCHEMBL6596123 | 0.70 | CCR1 (0.37) | CCR1ALDH1A1 | |
| SCHEMBL6599554 | 0.70 | GHSR (0.34) | CCR1ALDH1A1 | |
| SCHEMBL953000 | 0.69 | KMT2A (0.46) | KMT2ACCR1ALDH1A1LMNAALPG | |
| SCHEMBL29061981 | 0.69 | KMT2A (0.46) | KMT2ACCR1ALDH1A1LMNAALPG | |
| SCHEMBL6592377 | 0.69 | PBRM1 (0.39) | KMT2ACCR1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1311187 | 0.69 | CCR1 (0.43) | KMT2ACCR1ALDH1A1LMNAALPG | |
| SCHEMBL11854846 | 0.68 | CCR1 (0.43) | KMT2ACCR1ALDH1A1LMNAALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888336-A1 | NOVEL SUBSTITUTED N-METHYL-N-(4-(4-(1H-BENZIMIDAZOL-2-YL-AMINO)P IPERIDIN-1-YL)-2-(ARYL)BUTYL)BENZAMIDES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | HOECHST MARION ROUSSEL, INC. (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997030989-A1 | NOVEL SUBSTITUTED N-METHYL-N-(4-(4-(1H-BENZIMIDAZOL-2-YL-AMINO)PIPERIDIN-1-YL)-2-(ARYL)BUTYL)BENZAMIDES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | HOECHST MARION ROUSSEL, INC. (US) | 1997-08-28 | — | — | WO | disclosed |