Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.32 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.31 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.30 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.30 |
| ▸ | PRNP | P04156 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317275 | 0.84 | NPSR1 (0.34) | NPSR1KDM4EMAPT | |
| SCHEMBL8313504 | 0.78 | — | — | |
| SCHEMBL1977431 | 0.67 | MAPT (0.43) | PBRM1KDM4EMAPTGLACA1 | |
| SCHEMBL27652143 | 0.62 | KDM4E (0.48) | KDM4EGLAPTGDR2SRD5A1SRD5A2 | |
| SCHEMBL23362956 | 0.61 | CA1 (0.43) | NPSR1PBRM1MAPTCA1CA2 | |
| SCHEMBL29804089 | 0.61 | CA1 (0.43) | NPSR1PBRM1MAPTCA1CA2 | |
| SCHEMBL16291672 | 0.59 | HDAC3 (0.51) | KDM4ECA1CA2CA7CA9 | |
| SCHEMBL20213839 | 0.59 | KDM4E (0.53) | KDM4EMAPTPIM1GLAPTGDR2 | |
| SCHEMBL20587128 | 0.58 | MAPT (0.47) | PBRM1KDM4EMAPTGLACA1 | |
| SCHEMBL1979356 | 0.58 | KDM4E (0.59) | PBRM1KDM4EMAPTCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632033-B1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1999-04-07 | — | — | EP | disclosed |
| US-5646308-A | POTASSIUM CHANNEL ACTIVATORS USED AS ANTIASTHMATICS, ANTIEPILEPTICS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1997-07-08 | — | — | US | disclosed |
| EP-0632033-A1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-01-04 | — | — | EP | disclosed |