SCHEMBL831889

SCHEMBL831889

CCc1cc(Cc2cccc(C)c2N)cc(CC)c1N

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CD44 P16070 1/20 0.41
HTT P42858 2/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39
POLB P06746 1/20 0.38
DHFR P00374 4/20 0.37
GABRA1 P14867 2/20 0.36
GABRB2 P47870 2/20 0.36
ATP4A P20648 1/20 0.36
ATP4B P51164 1/20 0.36
NOS3 P29474 1/20 0.34
NOS1 P29475 1/20 0.34
NOS2 P35228 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29351040 0.82 CD44 (0.52) CD44HTTALDH1A1MAPTGABRA1
SCHEMBL755515 0.82 CD44 (0.52) CD44HTTALDH1A1MAPTGABRA1
SCHEMBL5016234 0.81 ALDH1A1 (0.40) CD44HTTALDH1A1MAPTDHFR
SCHEMBL14068526 0.81 ALDH1A1 (0.47) HTTALDH1A1MAPTPOLBDHFR
Hydrochloric Acid SCHEMBL7642490 0.81 CD44 (0.50) CD44HTTALDH1A1MAPTGABRA1
SCHEMBL11171247 0.81 CD44 (0.50) CD44HTTALDH1A1POLBGABRA1
SCHEMBL2247538 0.80 CD44 (0.54) CD44ALDH1A1POLBGABRA1GABRB2
SCHEMBL10805311 0.80 POLB (0.39) HTTALDH1A1MAPTPOLBDHFR
SCHEMBL29395088 0.79 ALDH1A1 (0.49) HTTALDH1A1MAPTPOLBDHFR
SCHEMBL48397 0.79 ALDH1A1 (0.49) HTTALDH1A1MAPTPOLBDHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3623870-B1 IMAGE FORMING APPARATUS AND TONER SET RICOH CO LTD (JP) 2022-05-04 EP disclosed
EP-3418811-B1 TONER, DEVELOPER, PROCESS CARTRIDGE, IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND METHOD FOR MANUFACTURING TONER RICOH CO LTD (JP) 2021-07-28 EP disclosed
EP-3144728-B1 TONER BINDER, AND TONER SANYO CHEMICAL IND LTD (JP) 2021-04-21 EP disclosed
US-10895816-B2 Image forming apparatus and toner set RICOH COMPANY, LTD. (JP) 2021-01-19 US disclosed
US-20210002441-A1 RESIN PARTICLES AND METHOD FOR PRODUCING SAME SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2021-01-07 US disclosed
US-20200089140-A1 IMAGE FORMING APPARATUS AND TONER SET RICOH COMPANY, LTD. (JP) 2020-03-19 US disclosed
EP-3623870-A1 IMAGE FORMING APPARATUS AND TONER SET Ricoh Company, Ltd. (JP) 2020-03-18 EP disclosed
US-10429756-B2 Toner, developer, process cartridge, image forming apparatus, image forming method, and method for manufacturing toner RICOH COMPANY, LTD. (JP) 2019-10-01 US disclosed
EP-2898371-B1 TONER, DEVELOPER, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH CO LTD (JP) 2019-09-11 EP disclosed
EP-3418811-A2 TONER, DEVELOPER, PROCESS CARTRIDGE, IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND METHOD FOR MANUFACTURING TONER Ricoh Company, Limited (JP) 2018-12-26 EP disclosed
US-4820743-A BLEND OF POLYETHERPOLYOL AND POLYAMINE, AND UNSATURATED MONOMER SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1989-04-11 US disclosed
EP-0245864-A2 Cyclohexanedimethanol/diamine mixtures as RIM extenders THE DOW CHEMICAL COMPANY (US) 1987-11-19 EP disclosed
EP-0219709-A2 Polymethylene polyphenylamine modified diamine chain extenders and polyurea elastomers therefrom THE DOW CHEMICAL COMPANY (US) 1987-04-29 EP disclosed
US-4659747-A HEAT RESISTANCE THE DOW CHEMICAL COMPANY (US) 1987-04-21 US disclosed
EP-0075130-B1 IMPROVED REACTION INJECTION MOLDING PROCESS THE DOW CHEMICAL COMPANY (US) 1986-09-17 EP disclosed
EP-0185369-A2 Polyamide-polyurea polymers THE DOW CHEMICAL COMPANY (US) 1986-06-25 EP disclosed
US-4552945-A REACTION INJECTION MOLDING, POLYURETHANES THE DOW CHEMICAL COMPANY (US) 1985-11-12 US disclosed
EP-0075130-A2 Improved reaction injection molding process THE DOW CHEMICAL COMPANY (US) 1983-03-30 EP disclosed
US-4374210-A MOLDING MATERIALS; LONG GELATION TIME; STOICHIOMETRY; INJECTION MOLDING THE UPJOHN COMPANY (US) 1983-02-15 US disclosed
US-4296212-A MOLDING MATERIALS THE UPJOHN COMPANY (US) 1981-10-20 US disclosed